产品货号：
Z20061
中文名称：
MAG抗体
英文名称：
Anti-MAG Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-MAG Antibody |
| 指标别名 | GMA;MAG;myelin associated glycoprotein;S MAG;SIGLEC 4A;SIGLEC4A |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | MAG |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human MAG (589-626aa EPPELDLSYSHSDLGKRPTKDSYTLTEELAEYAEIRVK),different from the related mouse sequence by one amino acid,and identical to the related rat sequence. |
| 实际分子量 | 100KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MAG (Myelin-associated glycoprotein),also known as SIGLEC4A,is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO-66 receptor,NgR.It is thought to be involved in the process of myelination.The MAG gene is mapped on 19q13.12.Cleavage of GPI-linked proteins from axons protects growth cones from MAG-induced collapse,and dominant-negative NgR eliminates MAG inhibition of neurite outgrowth.MAG-resistant embryonic neurons were rendered MAG-sensitive by expression of NgR.MAG binds specifically to an NgR-expressing cell line in a GPI-dependent and sialic acid-independent manner.Experiments blocking NgR from interacting with MAG prevented inhibition of neurite outgrowth by MAG.In cultured human embryonic kidney (HEK) cells expressing the NOGO receptor,p75(NTR) was required for MAG-induced intracellular calcium elevation. |
| Uniprot ID | P20916 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | myelin associated glycoprotein |
| 蛋白名全称 | Myelin-associated glycoprotein |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
相关搜索：MAG抗体，MAG多抗，Anti-MAG Antibody